Page 691 - e-Book
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of rhematic pains. A day by day dose of 1 ml/kg body weight of garlic Chemical structure of

               the energetic elements of Garlic. Medicinal fitness advantages of uncooked Garlic extract for
               sixth months can bring about significant discount in oxidant (unfastened radical) strain in the

               blood of patients with atherosclerosis and cholesterol circulating inside the blood flow. Garlic
               has ability to save you these oxidation reactions which may additionally give an explanation

               for some of its useful effects in atherosclerotic.
               Turmeric  (Curcuma  longa  L.)  belongs  to  the  own  family  of  ginger  (Zingiberaceae)  and

               natively grows in India and Southeast Asia. Rhizomes of this plant carries several secondary

               metabolites such as curcuminoids, sesquiterpenes, steroids, and polyphenol as most important
               bioactive materials. Omosa, Midiwo, & Kuete (2017). Curcumin is a herbal polyphenol that

               is remoted for turmeric (Curcuma longa) and has been used from centuries as a conventional

               remedy in Asian countries to treat various problems. Numerous research have shown that the
               curcumin  possesses  some  pharmacological  houses  which  includes  anti‐inflammatory,

               anti‐angiogenic,  and  anti‐neoplastic,  without  toxicity  meals  Drug  administration  (FDA)
               labeled it as “normally diagnosed as secure.” A dose of up to 12 g/day of curcumin become

               regarded  to  be  safe  for  human  consumption  at  some  stage  in  the  medical  trials  without
               displaying  any  aspect  outcomes.  Gupta,  Patchva,  &  Aggarwal,  (2013).  Shrivastava  (2020)

               mentioned  that  the  dose  of  curcumin  from  2,500  to  8000 mg  per  day  for  three  months

               confirmed  no  toxicity  from  curcumin.  Curcumin  is  a  dynamic  antiviral  that  reduces  the
               replication of viruses.

               Antiviral  activity  of  curcumin was  observed in  opposition to  exclusive viruses  along with
               hepatitis  viruses,  SARS  coronavirus,  influenza  viruses,  human  immunodeficiency  virus

               (HIV), herpes  simplex virus, dengue virus,  chikungunya virus. Curcumin's  antiviral  sports
               can also be evidenced with the aid of its ability to adjust numerous molecular goals that make

               a contribution to numerous cell events, inclusive of transcription law, and the activation of

               cellular  signaling  pathways.  Joe,  Vijaykumar  &  Lokesh  (2004).  Curcumin's  position  in
               focused  on  diverse  mobile  pathways,  in  addition  inhibiting  the  boom,  and  replication  of

               viruses  makes  it  a  perfect  candidate  as  an  anti‐viral  drug.  Utomo,  Ikawati,  and  Meiyanto

               (2020), based on their molecular docking observe, pronounced that the curcumin binds and
               inhibits the target receptors which include SARS‐CoV‐2 protease, spike glycoprotein‐RBD,

               and PD‐ACE2, which might be worried in virus infection.
               The  neem  tree  botanically  name    Azadirachta  indica  is  a  fast‐growing  evergreen  herb

               belonging to the family Meliaceae. The Indian origin ancient medicinal plant neem has been
               used to treat several types of acute and chronic diseases in different parts of Asia and Africa




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