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from the ancient period. All different parts of the neem tree such as seeds, roots, leaves,

flowers, and bark have been used in traditional medicine as household remedies against
various human ailments. They showcase antimicrobial, larvicidal, antimalarial, antibacterial,

antiviral, and spermicidal effects. Gupta et al., (2013).
Unique terpenoids isolated from the bark of this herb consist of nimbin, nimbidin, nimbolide,

limonoids, β‐sistosterol, 6‐desacetylnimbinene, nimbione, margocin, and so on. Alzohairy,
(2016). A compound from the extract of neem leaves called “hyperoside” possesses exact

ability as a universal drug towards influenza lines because of its loose radical scavenging

belongings. Hyperoside compound from neem leaf extract at the side of the chemical tablets
LGH, Naproxen, BMS‐885838, and BMS‐883559 confirmed quality consequences with

conserved residues of nucleoprotein of influenza virus. Ahmad et al.,(2016). The neem is a

great plant and a United country has declared neem as the “tree of the twenty first century”
United nations surroundings Programme, (2012). Due to its already proven antiviral

residences and effectiveness, many scientists have began studies on neem for discovering
capsules in opposition to SARS‐COV‐2. Herbal bioactive compounds, specifically, methyl

eugenol, and ursolic acid extracted from tulsi and neem act as inhibitors towards
SARS‐CoV‐2. These bioactive compounds function as powerful inhibitors of SARS‐CoV‐2

through binding to the spike glycoprotein, RNA polymerase, and or its protease which ends

up inside the prevention of both viral attachment and replication. Kumar, (2020). About 20
compounds remoted from neem leaves extract confirmed high binding affinity in opposition

to COVID‐19 fundamental protease protein which is the key protein for viral replication.
Subramanian , (2020).

Ginger (Zingiber officinale) has healing homes in opposition to pulmonary fibrosis,
pneumonia, ARDS, sepsis, and acute kidney injury. In addition, ginger at the side of its

phytochemicals has antiviral, ant fibrotic, antioxidant and anti-inflammatory. Chang, Wang,

Yeh, Shieh & Chiang, (2013); Mao et al., (2019); Rahmani , Shabrmi & Aly (2014).
Ginger has notably decreased pulmonary fibrosis and mitigated oxidative pressure and

inflammatory response in chemically brought about pulmonary fibrosis in animal models. for

example, bleomycin, a cytotoxic antibiotic utilized in cancer remedy, has idiopathic
pulmonary fibrosis (IPF) as an aspect effect. In bleomycin‐dealt with rats, zingerone, a

bioactive compound in ginger has extensively decreased fibrosis rating in histopathological
sections of lungs, decreased ranges of fibrosis marker, hydroxyproline and oxidative pressure

marker, and malondialdehyde (MDA). in addition, it increased ranges of antioxidant markers
like reduced glutathione (GSH), superoxide dismutase (SOD), and glutathione peroxidase

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