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Study screening and selection

               A stepwise procedure in the form of a flowchart diagram of literature searches and inclusion
               and exclusion method of the articles is presented in Fig. 1. For this purpose, the title, abstract,

               and main body of the article of interest were studied, evaluated and selected based on certain
               defined criteria.

               Inclusion criteria
               The articles to be included in the review must meet all the inclusion criteria which were: 1)

               Reviews,  research  articles,  and  book  chapters  only  on  walnut,  2)  the  formulations/key

               ingredients  of plant extracts  used against various  diseases  and ailments  were reported  and
               included in the present study to finalize the walnut plant that are extensively used in such

               herbal  formulations,  3) research articles that are  only focused on the  in  vitro  studies   and

               phytochemical analysis, 4) the articles published only in English journals and containing the
               maximum relevant information.

               Exclusion criteria
               The  exclusion  criteria  of  the  data  for  this  study  were  well-defined  as  1)  Duplicates  was

               excluded, 2) Article not relevant to the topic, 3) Articles having not clear results, 4) Articles
               having not sufficient data.

               Ethnomedicinal survey

               An ethnomedicinal survey had been conducted in Ramban and other district areas which are
               major  production  areas  of  walnut.  Some  open-end  and  semi-structured  interviews  were

               carried out to document the traditional knowledge and uses of walnut by medicine men and
               local peoples of these areas .

               Results
               According to the above-mentioned search strategy and selection criteria, firstly, 650 search

               results were identified via electronic databases and reviewed based on the title and abstract.

               After the screening of relevant records by title and abstract, we just removed unsuitable and
               identical articles. 455 articles did not meet the set inclusion criteria so that was excluded and

               finally 195 articles selected as they met all set inclusion criteria and containing the maximum

               relevant information. The complete information on the various parameters like morphology,
               ethnomedicinal uses, phytochemistry and pharmacology are studied. Field surveys and semi-

               structured interviews were carried to elicit secret traditional knowledge from locals inhabiting
               and herbalists in accessible areas of the regions in J&K UT. Appropriate methodology was

               followed  during  the  present  study  usually  the  survey  in  each  locality  started  with  the
               interviews  of  elderly  and  experienced  members  of  locality,  herbalists  and  medicine  men.



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