Page 77 - e-Book
P. 77
3.3.2. SGPT
S.No. Treament SGPT (IU/L)
1. Control 107.375
2. CCl4 114.725
3. 200mg + CCl4 107.325
4. 400mg+CCl4 96.36
SGPT
120
114.72
115
110 107.37 107.32
105
100
96.36
95
90
85
Control CCl4 200mg 400mg
Treament Group
4. DISCUSSION
In the investigation preliminary qualitative phytochemical analysis of the aqueous extracts of
Cassia tora seed and its fraction indicates the presence of carbohydrates, alkaloids,
flavanoids, antraquinone, fats, saponins and phenolic compounds. Cassia tora seed extract
has rich quantity of polyphenol and other component with significant antioxidant activity.
Antraquinone, flavanoids, saponins and glycosides are well known for their anti-oxidant and
hepatoprotective activitys. Thus present study was designed to assess hepatoprotective
activity of cassia tora seed extract against carbon tetra chloride (CCl4) induces
hepatotoxicity. Test sample cassia tora seed extract showed significant hepatoprotective
potential. In vitro antioxidant activity was performed using DPPH assay and reducing power
assay. DPPH assay showed that extract exhibits 131.771 percent of inhibition. The
investigation shows that the seed extract are rich in antioxidant activity. In vivo antioxidant
67