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activity was performed using Lipid peroxidase. LPO Showed increase activity of treating
group. There was significant elevation of SGOT and SGPT bilirubin levels (221.025 and
114.75 v/s 105.35 and 107.37 in control) respectively in the carbon tetra chloride treated
groups. In groups orally treated with aqueous extracts of cassia tora seed above activities of
enzyme were found to be significantly decreased as compare to the carbon tetra chloride
treated group and the treatment group treated with 400mg/kg body weight of extract showed
the levels near to control suggesting a very little damage due to inducer. Morphological
observation showed an increased in size in carbon tetra chloride treated groups, this may be
due to the necrosis of the hepatic cells. These changes were reversed by treated with Cassia
tora seed extract at dose tested. Our study supports the earlier study done on hepatoprotective
activity of Cassia tora seeds by Surana et. al. (2012).
5. CONCLUSION
Based on above research work it can be concluded that Cassia tora seeds can be the good
source for the medicinal drug and should be explored further. Future work also includes the
further purification of the metabolites responsible for hepatoprotective properties using
sophisticated purification procedures. The present work signifies the important role that
Cassia tora’s various plant parts including seeds can play in our well-being. The status quo of
this plant needs to be changed from being a weed to being cultivated plant. This plant holds
great treasure for development of various ethanopharmacological drugs.
6. References
Aquino, R., Morelli, S., Lauro, M. R., Abdo, S., Saija, A., & Tomaino, A. (2001). Phenolic
constituents and antioxidant activity of an extract of anthurium v ersicolor
leaves. Journal of Natural Products, 64(8), 1019-1023.
B. Ballabh and O. P. Chaurasia, (2007). “Traditional medicinal plants of cold desert Ladakh-
Used in treatment of cold, cough and fever,” Journal of Ethnopharmacology, vol. 112,
no. 2, pp. 341–345.
de Ancos, B., González, E. M., & Cano, M. P. (2000). Ellagic acid, vitamin C, and total
phenolic contents and radical scavenging capacity affected by freezing and frozen
storage in raspberry fruit. Journal of agricultural and food chemistry, 48(10), 4565-
4570.
Evans, W. C. (2009). Trease and evans' pharmacognosy E-book. Elsevier Health Sciences.
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