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Antihelmenthic activity

               Acetone extract from walnut bark possesses significant activity against Eicinia feotida. Also,
               ethanol,  methanol  and  benzene  extract  of  bark  showed  significant  antihelmenthic  activity

               against  Pheretima  posthumana  and  concluded  that  stem  bark  has  a  maximum  an
               antihelmenthic activity (Upadhyay et al., 2010a).

               Hepatoprotective activity
               Some researchers reported that walnut polyphenols from kernel pellicle orally given to liver

               damaged in mice model induced by CCL4.  This result showed that polyphenols are higher

               hepatoprotective agent than commonly used famous curcumin. It was found that polyphenolic
               constituents were the main principal phytoconstituents present in different parts of walnut are

               responsible against oxidative damage for hepatoprotective activity. Tellimagrandins I one of

               the polyphenolic was found as the vital constituents as hepatoprotective agent (Hiroshi et al.,
               2008).

               Anticancer activity
               Anticancer  properties  had  been  reported  Juglone  as  a  promising  chemo  preventive  agent

               against many cancerous cells. Researcher had done a invitro study revealed juglone as potent
               cytotoxic agent against human tumor cell lines. Juglone induced apoptosis and inhibited the

               growth  of  sarcoma  cells  (Ji  et  al.,  2011).  Walnut  leaf,  bark,  green  husk,  fine  powder  as

               petroleum  and  methanolic  extract  shows  significant  anticancer  properties  by  growth
               inhibition, antiproliferative efficiency, activation of mitochondrial death pathway, generation


               of reactive oxygen species (ROS) mechanisms (Kumudhavalli et al., 2010).
               Memory booster activity

               Walnut enhancing the memory and learning skills and act as memory booster was reported
               and concluded that it increases serotonin level in the brain which result into the advancement


               in  memory  and  learning  capacity (Haider,  2011;  Asadi-Shekaari,  2013).  One  more  study
               conducted  showed  the  effect  of  polyphenol  extracts  from  green  husk  and  kernels
               magnificently increases the learning and memory function of brain (Eidi, 2013; Shi, 2014).

               Immunity booster activity

               It  has  been  reported  that  fruits  of  walnut  increases  and  boosts  the  immunity  of  immune
               system by increasing phagocytosis against various macrophages and enhancing proliferations

               of lymphocytes (Ruijun, 2015). Hence, due to its immune boosting activity walnut can be one
               of the key medicinal plant used in Covid-19 viral infections also.






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