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accepted (Praditya et al., 2019). It inhibits the entry of hepatitis C, Zika and Chikungunya,

Influenza A, Japanese encephalitis, Murine norovirus, and Respiratory syncytial viruses into
the host cells (Praditya et al., 2019). The inhibition of the viral replication of hepatitis B virus

and hepatitis C virus by curcumin is previously reported (Wei et al., 2017). These results
show some hope for the utilization of curcumin for the management of COVI-19. The

combination of Artemisinin, Curcumin, Frankincense, and vitamin C for the management of
COVID-19 patients is under investigation (NCT04382040).

Saikosaponins, epigallocatechin 3-gallate, Pelargonium sidoides extract, tannins from

Terminalia chebula and cimicifugin from Cimicifuga foetida are reported to block the viral
entry of Coronavirus, hepatitis C virus, IFA, dengue, and Measles viruses respectively (Lin,

Hsu, & Lin, 2014). Similarly, Chebulagic acid and punicalagin (tannins isolated from

Terminalia chebula) also inhibit the entry of many viruses especially DENV (Lin et al.,
2014). Ocimum basilicum (sweet basil), Flavone baicalein, Epigallocatechin gallate (green

tea), Ent-epiafzelechin-(4α→8)-epiafzelechin (Cassia javanica), and tricyclic coumarin
(Calophyllum brasiliense) blocks the replication of Coxsackie B virus type 1, dengue viruses,

Enterovirus, Herpes simplex viruses, and HIV respectively (Lin et al., 2014).
CONCLUSION AND FUTURE PERSPECTIVE

From the initial phase to date during this COVID-19 pandemic, the Ayurveda have attracted

the common persons, researchers, medical experts, political leaders, and regulatory bodies for
their significance to fight the diseases. When there is no drug is known to target SARS-CoV-

2, people are advised to take Ayurvedic decoction and natural plant products as precautionary
steps. And Mother Nature in the form of these active ingredients has indeed strengthened our

fight against COVID-19. And it is easily visible that the consumption of Ayurvedic or natural
plant products has been increased significantly during this period. Their immune booster

potential and wide range of immunological activities are globally accepted and highly

recommended. Coronaviruses like HCoV-22E9 and SARS-CoV can be easily treated by such
plant products. For example, polyphenols, terpenes, and saponins extracted from various

plants have virucidal activities. Saponins are being used as natural detergents to disrupt the

lipid‐based envelope of the virus (Lin et al., 2014).
The demand for various antiviral mouthwash is increased so that it can kill the virus in the

mouth and eradicate it from the body well before it enters into the lungs. It is suggested that
Curry leaves (Murraya koenigii L. Spreng) can be a natural mouth wash as it contains

polyphenols, terpenes, saponins, chlorophyll, and carotene. It is reported that the mouthwash
with Curry-leaf is highly effective against plaque-induced gingivitis (Varghese, Babu, &

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